Stem Cell Therapy vs PRP: What’s the Difference?

February 20, 2023

As chronic pain sufferers explore non-surgical treatments, they may come across two promising therapies – stem cell and platelet rich plasma (PRP). Both offer potential benefits for a variety of conditions, but how do these approaches differ?

In this article we will look at both stem cell and PRP therapies in detail, compare them side by side to understand their differences, and discuss safety considerations. Whether you’re considering one or both options as part of your treatment plan, it is important to have an understanding of each before making any decisions. So let’s take a closer look at stem cell therapy vs PRP.

Table of Contents:

What is Stem Cell Therapy?

Stem cell therapy is a form of regenerative medicine that employs stem cells to repair and substitute damaged or diseased tissues. Stem cells are special types of cells that have the ability to divide and differentiate into different types of specialized cells, such as heart muscle, nerve, or bone. Stem cells’ capacity to differentiate into specialized tissue makes them a prime candidate for treating conditions like chronic pain, arthritis, tendonitis, joint harm and spinal cord injuries.

Definition of Stem Cells

Unspecialized cells that can divide and evolve into multiple cell forms with certain purposes in the body are termed stem cells. Adult and embryonic tissues both contain stem cells, such as those found in skin or umbilical cord. Embryonic stem cells possess the capacity to differentiate into any kind of cell in an organism, whereas adult stem cells are limited to generating particular kinds of specialized cells within their own tissue type.

There are two main categories of stem cells:

embryonic stem (ES)cells and adult stem (AS)cells. EScells come from embryos at four-to-five days old while AScells come from various parts of an adult’s body including bone marrow, fat tissue, peripheral blood vessels etc. Both ES and AScell therapies offer promising treatments for many diseases due to their ability to differentiate into other specialized cell types when stimulated by growth factors or cytokines released by surrounding tissues during injury/disease processes.

Benefits Of Stem Cell Therapy

Stem cell therapy has the capacity to offer a reprieve from long-term ache, being an inventive and encouraging treatment option. By understanding what PRP therapy is, you can determine which of these two treatments may be best suited for your needs.

Key Takeaway: Stem cell therapy offers potential treatments for a variety of ailments, due to its capacity to morph into distinct cellular forms and furnish restorative gains.

What is PRP Therapy?

PRP Therapy, or Platelet Rich Plasma therapy, is a non-surgical approach to healing that uses the body’s own platelets and plasma to help heal damaged tissue. PRP therapy works by harvesting a patient’s blood and spinning it in a centrifuge to separate out the platelets from other components of the blood. The concentrated platelets are then injected into an injured area of the body with ultrasound guidance for precise placement.

PRP therapy is a regenerative approach that harnesses the power of growth factors found within one’s own platelets, for the purpose of stimulating healing and regeneration in areas where trauma has occurred. It can be used for many different types of injuries including tendonitis, ligament sprains/strains, muscle tears, arthritis pain relief, joint pain relief, and more.

Once injected into an area with injury or inflammation, this solution helps to stimulate new cell growth while also providing natural anti-inflammatory properties. This solution offers a more effective, longer-term relief from discomfort and swelling than the conventional methods of corticosteroid injections or surgery.

PRP treatment has been explored as a potential solution for numerous health issues, with the possibility of offering various advantages. However, it is crucial to evaluate how PRP stacks up against other treatments such as stem cell therapy so as to decide which treatment plan will be most beneficial for the individual.

Key Takeaway: PRP, a non-invasive method of healing, utilizes the body’s own platelets and plasma to induce recovery, decrease inflammation, and afford enduring comfort.

Comparing Stem Cell vs PRP Therapies

Stem cell and PRP therapies are two of the most popular treatments for chronic pain. Both treatments offer potential relief from a variety of conditions, but they have different approaches to healing. Comprehending the commonalities and discrepancies between these two therapies can assist in selecting a suitable treatment for your circumstances.


Both stem cell therapy and PRP therapy involve injecting cells or growth factors into the body to stimulate healing. Both treatments utilize natural elements present in the organism, thus eliminating any potentiality of introducing alien materials into one’s body. Additionally, both therapies necessitate multiple meetings across a span of time to accomplish the desired outcomes.


Stem cell therapy involves extracting adult stem cells from bone marrow before injecting them back into areas where healing is needed. The injected stem cells then differentiate into specialized cells that promote regeneration and repair damaged tissues in those areas.

On the other hand, PRP therapy involves taking a sample of blood from the patient’s arm and spinning it in a centrifuge to separate out platelets with high concentrations of growth factors that promote healing when injected back into affected areas.

Stem cell therapy has been used to successfully treat a variety of conditions, such as arthritis, tendonitis, ligament injuries, cartilage damage and muscle tears/strains/sprains. On the other hand, PRP has been found to be effective for similar issues like tendinopathies (tendon disorders), plantar fasciitis (foot pain) and rotator cuff injuries (shoulder).

However, due to its ability to stimulate new tissue formation through differentiation of stem cells directly at injection sites rather than relying on inflammation like PRP does; stem cell injections may be more suitable for some conditions such as spinal cord injury or stroke recovery.

Meanwhile, PRP might be better suited for treating musculoskeletal issues such as tennis elbow or Achilles tendonitis due its anti-inflammatory properties which reduce swelling quickly allowing injured muscles/tendons/ligaments heal faster by reducing strain on them during movement activities.

Comparing stem cell and PRP therapies can be a tricky business, but with some insight into their commonalities and differences, the potential risks associated with each option, as well as cost evaluations – you can make an educated choice about which therapy is most appropriate for your personal requirements. Now let’s take a closer look at safety considerations when it comes to these two treatments.

Key Takeaway: Stem cell and PRP therapies offer different approaches to healing, with stem cells stimulating new tissue formation while PRP reduces inflammation; making them suitable for different conditions.

Safety Considerations for Both Treatments

Comprehending the safety aspects linked to each of these treatments is imperative before opting for a particular option, as both have potential advantages.

Potential Side Effects and Risks Involved with Each Treatment Option: Stem cell therapy involves injecting stem cells into the affected area of the body to promote healing. Though generally thought to be secure, certain hazards may still occur with stem cell therapy such as infection, harm to nerves and possible tissue death.

PRP therapy involves taking a sample of your own blood and spinning it in a centrifuge to separate out platelets containing growth factors that can help stimulate healing. The main risk associated with this procedure is an allergic reaction to the injected material or an infection at the injection site.

Prior to initiating either treatment, it is recommended that patients consult with their medical provider regarding any current medications or health conditions as these may influence the efficacy of the treatments and cause adverse reactions during sessions.

During both types of treatments you will likely experience some discomfort from injections but should not feel any long-term pain afterwards if done correctly by a trained professional. After treatment sessions have concluded most people report feeling relief within 1-2 weeks although full results may take up to 6 months depending on severity of condition being treated.

Key Takeaway: Stem cell and PRP therapies offer potential benefits, but it is important to understand the risks involved with each one before making a decision.


When it comes to managing chronic discomfort, stem cell treatment and PRP therapy are two of the most encouraging solutions available. Both therapies present possible advantages for those enduring persistent discomfort, yet there are essential variations between them which should be considered prior to settling on a choice.

Stem cell therapy is best suited for conditions such as arthritis, tendonitis, and ligament injuries while PRP is better for muscle tears or joint sprains. Ultimately, it is essential to weigh the pros and cons of each approach with your physician in order to make an informed decision regarding which treatment would be most beneficial for you.

Are you looking for a solution to improve your overall health and wellness? Total Stem Cell provides advanced stem cell therapies such as PRP, Stem Cell, MLS, and Hair restoration that can help. Our experts are here to answer any questions you may have about these treatments so don’t hesitate – take the first step towards bettering yourself today!